Efficacy of branched chain amino acids supplementation in liver cirrhosis: A systematic review and meta-analysis
Georgios Konstantis, Chryssa Pourzitaki , Michail Chourdakis, Elisavet Kitsikidou,Georgios Germanidis Δείτε ΕΔΩ το άρθρο
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How Far beyond Diabetes Can the Benefits of Glucagon-like Peptide-1 Receptor Agonists Go? A Review of the Evidence on Their Effects on Hepatocellular Carcinoma
Review Konstantinos Arvanitakis 1,2 , Theocharis Koufakis 3 , Kalliopi Kotsa 3 and Georgios Germanidis 1,2 1 First Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki,54636 Thessaloniki, Greece2 Basic and Translational Research Unit (BTRU) of Special Unit for Biomedical Research and Education(SUBRE), School of Medicine, Faculty of Health Sciences, Aristotle University of…
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Tumor-Associated Neutrophils in Hepatocellular Carcinoma Pathogenesis, Prognosis, and Therapy
Review Konstantinos Arvanitakis 1,2, Ioannis Mitroulis 3 and Georgios Germanidis 1,2,* 1 First Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki,54636 Thessaloniki, Greece; kostarvanit@gmail.com2 Basic and Translational Research Unit, Special Unit for Biomedical Research and Education, School ofMedicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece3 First Department of…
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Clinical, histological and molecular profiling of different stages of alcohol-related liver disease
Ventura-Cots M, Argemi J, Jones PD, Lackner C, El Hag M, Abraldes JG, Alvarado E, Clemente A, Ravi S, Alves A, Alboraie M, Altamirano J, Barace S, Bosques F, Brown R, Caballeria J, Cabezas J, Carvalhana S, Cortez-Pinto H, Costa A, Degré D, Fernandez-Carrillo C, Ganne-Carrie N, Garcia-Tsao G, Genesca J, Koskinas J, Lanthier N,…
ΛεπτομέρειεςHepatitis Viruses Control Host Immune Responses by Modifying the Exosomal Biogenesis Pathway and Cargo
Karamichali E, Foka P, Papadopoulou G, Loukaki-Gkountara D, Andresaki K, Koskinas I, Georgopoulou U. Int J Mol Sci. 2022 Sep 17;23(18):10862. doi: 10.3390/ijms231810862. PMID: 36142773; PMCID: PMC9505460
ΛεπτομέρειεςPharmacotherapy for Non-alcoholic Fatty Liver Disease Associated with Diabetes Mellitus Type 2
Koullias ES, Koskinas J. J Clin Transl Hepatol. 2022 Oct 28;10(5):965-971. doi: 10.14218/JCTH.2021.00564. Epub 2022 May 30. PMID: 36304499; PMCID: PMC9547270
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Cellular, Molecular and Proteomic Characteristics of Early Hepatocellular Carcinoma
Armakolas A, Dimopoulou V, Nezos A, Stamatakis G, Samiotaki M, Panayotou G, Tampaki M, Stathaki M, Dourakis S, Koskinas J. Curr Issues Mol Biol. 2022 Oct 10;44(10):4714-4734. doi: 10.3390/cimb44100322. PMID: 36286037; PMCID: PMC9600540.
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Coordinated activation of TGF-β and BMP pathways promotes autophagy and limits liver injury after acetaminophen intoxication
Stavropoulos A, Divolis G, Manioudaki M, Gavriil A, Kloukina I, Perrea DN, Sountoulidis A, Ford E, Doulou A, Apostolidou A, Katsantoni E, Ritvos O, Germanidis G, Xilouri M, Sideras P. Sci Signal. 2022 JunClick here to read the article
Neutrophil extracellular traps enriched with IL‑1β and IL‑17A participate in the hepatic inflammatory process of patients with non‑alcoholic steatohepatitis
Neutrophil extracellular traps (NETs) are implicated in the pathogenesis of various non-infectious inflammatory and thrombotic diseases. We investigated the presence and possible associations of NETs with various histopathologic parameters in patients with non-alcoholic steatohepatitis (NASH). We retrospectively assessed 20 liver biopsy specimens from patients with non-alcoholic fatty liver disease (NAFLD), including 17 specimens with NASH,…
ΛεπτομέρειεςConsensus recommendations for histological criteria of autoimmune hepatitis from the International AIH Pathology Group
Diagnostic histological criteria for autoimmune hepatitis (AIH) have not been clearly established. Previously published criteria focused mainly on chronic AIH, in which inflammatory changes mainly occur in portal/periportal regions and may not be applicable to acute presentation of AIH, in which inflammatory changes are typically predominantly lobular in location. International consensus criteria for the diagnosis…
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