Severe acute liver disease in adults: Contemporary role of histopathology

Clouston A D, Gouw A S H, Tiniakos D, Bedossa P, Brunt E M, Callea F, Dienes H-P, Goodman Z D,Hubscher S G, Kakar S, Kleiner D E, Lackner C, Park Y N, Roberts E A, Schirmacher P, Terracciano L,Torbenson M, Wanless I R, Zen Y & Burt A D(2024) Histopathology. https://doi.org/10.1111/his.15212 ΕΔΩ μπορείτε να…

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How Far beyond Diabetes Can the Benefits of Glucagon-like Peptide-1 Receptor Agonists Go? A Review of the Evidence on Their Effects on Hepatocellular Carcinoma

Review Konstantinos Arvanitakis 1,2 , Theocharis Koufakis 3 , Kalliopi Kotsa 3 and Georgios Germanidis 1,2 1 First Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki,54636 Thessaloniki, Greece2 Basic and Translational Research Unit (BTRU) of Special Unit for Biomedical Research and Education(SUBRE), School of Medicine, Faculty of Health Sciences, Aristotle University of…

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Tumor-Associated Neutrophils in Hepatocellular Carcinoma Pathogenesis, Prognosis, and Therapy

Review Konstantinos Arvanitakis 1,2, Ioannis Mitroulis 3 and Georgios Germanidis 1,2,* 1 First Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki,54636 Thessaloniki, Greece; kostarvanit@gmail.com2 Basic and Translational Research Unit, Special Unit for Biomedical Research and Education, School ofMedicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece3 First Department of…

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Clinical, histological and molecular profiling of different stages of alcohol-related liver disease

Ventura-Cots M, Argemi J, Jones PD, Lackner C, El Hag M, Abraldes JG, Alvarado E, Clemente A, Ravi S, Alves A, Alboraie M, Altamirano J, Barace S, Bosques F, Brown R, Caballeria J, Cabezas J, Carvalhana S, Cortez-Pinto H, Costa A, Degré D, Fernandez-Carrillo C, Ganne-Carrie N, Garcia-Tsao G, Genesca J, Koskinas J, Lanthier N,…

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Coordinated activation of TGF-β and BMP pathways promotes autophagy and limits liver injury after acetaminophen intoxication

Stavropoulos A, Divolis G, Manioudaki M, Gavriil A, Kloukina I, Perrea DN, Sountoulidis A, Ford E, Doulou A, Apostolidou A, Katsantoni E, Ritvos O, Germanidis G, Xilouri M, Sideras P. Sci Signal. 2022 JunClick here to read the article

Neutrophil extracellular traps enriched with IL‑1β and IL‑17A participate in the hepatic inflammatory process of patients with non‑alcoholic steatohepatitis

Neutrophil extracellular traps (NETs) are implicated in the pathogenesis of various non-infectious inflammatory and thrombotic diseases. We investigated the presence and possible associations of NETs with various histopathologic parameters in patients with non-alcoholic steatohepatitis (NASH). We retrospectively assessed 20 liver biopsy specimens from patients with non-alcoholic fatty liver disease (NAFLD), including 17 specimens with NASH,…

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