How Far beyond Diabetes Can the Benefits of Glucagon-like Peptide-1 Receptor Agonists Go? A Review of the Evidence on Their Effects on Hepatocellular Carcinoma

Νέα, Ανακοινώσεις, Εργασίες Ελλήνων ιατρών

Review Konstantinos Arvanitakis 1,2 , Theocharis Koufakis 3 , Kalliopi Kotsa 3 and Georgios Germanidis 1,2 1 First Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki,54636 Thessaloniki, Greece2 Basic and Translational Research Unit (BTRU) of Special Unit for Biomedical Research and Education(SUBRE), School of Medicine, Faculty of Health Sciences, Aristotle University of…

Tumor-Associated Neutrophils in Hepatocellular Carcinoma Pathogenesis, Prognosis, and Therapy

Νέα, Ανακοινώσεις, Εργασίες Ελλήνων ιατρών

Review Konstantinos Arvanitakis 1,2, Ioannis Mitroulis 3 and Georgios Germanidis 1,2,* 1 First Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki,54636 Thessaloniki, Greece; kostarvanit@gmail.com2 Basic and Translational Research Unit, Special Unit for Biomedical Research and Education, School ofMedicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece3 First Department of…

Clinical, histological and molecular profiling of different stages of alcohol-related liver disease

Νέα, Ανακοινώσεις, Εργασίες Ελλήνων ιατρών

Ventura-Cots M, Argemi J, Jones PD, Lackner C, El Hag M, Abraldes JG, Alvarado E, Clemente A, Ravi S, Alves A, Alboraie M, Altamirano J, Barace S, Bosques F, Brown R, Caballeria J, Cabezas J, Carvalhana S, Cortez-Pinto H, Costa A, Degré D, Fernandez-Carrillo C, Ganne-Carrie N, Garcia-Tsao G, Genesca J, Koskinas J, Lanthier N,…

Coordinated activation of TGF-β and BMP pathways promotes autophagy and limits liver injury after acetaminophen intoxication

Νέα, Ανακοινώσεις, Εργασίες Ελλήνων ιατρών, Ερευνητικά πρωτόκολλα

Stavropoulos A, Divolis G, Manioudaki M, Gavriil A, Kloukina I, Perrea DN, Sountoulidis A, Ford E, Doulou A, Apostolidou A, Katsantoni E, Ritvos O, Germanidis G, Xilouri M, Sideras P. Sci Signal. 2022 JunClick here to read the article

Neutrophil extracellular traps enriched with IL‑1β and IL‑17A participate in the hepatic inflammatory process of patients with non‑alcoholic steatohepatitis

Εργασίες Ελλήνων ιατρών

Neutrophil extracellular traps (NETs) are implicated in the pathogenesis of various non-infectious inflammatory and thrombotic diseases. We investigated the presence and possible associations of NETs with various histopathologic parameters in patients with non-alcoholic steatohepatitis (NASH). We retrospectively assessed 20 liver biopsy specimens from patients with non-alcoholic fatty liver disease (NAFLD), including 17 specimens with NASH,…

Consensus recommendations for histological criteria of autoimmune hepatitis from the International AIH Pathology Group

Εργασίες Ελλήνων ιατρών

Diagnostic histological criteria for autoimmune hepatitis (AIH) have not been clearly established. Previously published criteria focused mainly on chronic AIH, in which inflammatory changes mainly occur in portal/periportal regions and may not be applicable to acute presentation of AIH, in which inflammatory changes are typically predominantly lobular in location. International consensus criteria for the diagnosis…